Disruptive and Novel Therapeutics for Oncology Indications
20 Jan 2023
09:00
Patient and Clinical Considerations Track
9:00am Chair Introduction
Ana Rosa Sáez Ibáñez, Research Analyst, Cancer Research Institute
9:05am Presentation: NK Cells Impacting Oncology Pipelines
- Off-the-shelf is a minmum
- Potency is crucial
Troels Jordansen, Chief Executive Officer, Glycostem Therapeutics
9:20am Presentation: The Innovator’s Dilemma for Cancer Therapies: Going from ‘Novel’ to ‘Disruptive’
- Most advanced therapies are novel, but not yet disruptive in the marketplace.
- Disruptive innovation requires success across the clinical value chain from cross-disciplinary teams.
- Once we become disruptive, how do we stay disruptive?
Anne Cox, Director of Business Development, Tensentric
9:35am Presentation: Overcoming the Misconception of CAR-T’s for Solid Tumors
- CAR-T Signaling Refinements designed for Solid tumors
- Evidence of Early Success
- The Luminary Approach
- An allogeneic manufacturing chassis for Solid Tumors
Jeff Liter, Chief Executive Officer, Luminary Therapeutics
9:50am Presentation: Scalable Manufacture of CAR-NK Cells from Engineered Pluripotent Stem Cells with 3-D Bioreactor
- A proprietary scalable 3D iPS-NK manufacture platform with defined, serum-free and feeder-free conditions: pure and strong functional iPS-NK with CD8+ effector cell identity for immunotherapy
- Establishment of permanent, stable, genetically-engineered and clonal iPS-CAR lines for the manufacture of unlimited homogenous CAR-NK cells from multiple master iPS-CAR cell banks
- Development of next-generation 3D bioreactor platform and logistics: the ultimate goal of making CAR-NK products affordable and available for ordinary patient
Allen Feng, Chief Scientific Officer, HebeCell
10:05am Closing Panel with Q&A
With all session participants